Individual Response Variations to Erythropoietin Stimulating Agents in Patients on Maintenance Hemodialysis.
نویسندگان
چکیده
منابع مشابه
Current Anemia Treatment in Hemodialysis Patients: The Challenge for Secure Use of Erythropoietin-Stimulating Agents
Anemia is the poor capacity of blood to carry oxygen. Anemia is diagnosed by measuring hemoglobin (HB) level (g/dL) and hematocrit (HT) (percentage of erythrocytes in the blood). Normal limits vary in the general population [1]. According to the World Health Organiza‐ tion, normal HB is defined as 13 g/dL in men and 12 g/dL in women [2]. In clinical practice, HB lower than 11 g/dL is widely acc...
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Anemia in chronic kidney disease (CKD) is common, causing morbidity and mortality, and is primarily due to reduced erythropoietin (EPO) release and, to a lesser degree, shortened red cell survival. Erythropoietin Stimulating Agents like epoetin Alfa and darbepoetin alpha are used commonly to treat this form of anemia. Recent evidence suggests increased morbidity and mortality associated with hi...
متن کاملVitamin C plasma level and response to erythropoietin in patients on maintenance haemodialysis.
BACKGROUND Intravenous vitamin C supplementation to haemodialysis patients might ameliorate responsiveness to recombinant human erythropoietin (rHuEpo). This study was performed to analyse the relation between vitamin C plasma concentration and response to rHuEpo. METHODS In a cross-sectional, single-centre observational study including all haemodialysis patients, pre-dialysis plasma vitamin ...
متن کاملthe relationship between erythropoietin resistance and antibody response to hepatitis b vaccine in hemodialysis patients
conclusions epo resistance was negatively associated with anti-hbs levels and seroconversion. more studies are needed to highlight the underlying mechanisms regarding epo resistance and response to hbv vaccination in hd patients. results in total 97 patients were enrolled. for the entire group, stepwise linear regression analysis revealed that square root transformed anti-hbs levels were indepe...
متن کاملResistance to Erythropoiesis-Stimulating Agents Is Associated with Arterial Microcalcification in Early Hemodialysis Patients
The aim of this study was to evaluate the relationship between arterial microcalcification (AMiC) and erythropoiesis-stimulating agents (ESA) hyporesponsiveness in hemodialysis patients. The presence of AMiC was confirmed by pathologic examination of von Kossa-stained arterial specimens acquired during vascular access surgery. We assessed the ESA hyporesponsiveness index (EHRI), defined as the ...
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ژورنال
عنوان ژورنال: IOSR Journal of Pharmacy and Biological Sciences
سال: 2017
ISSN: 2319-7676,2278-3008
DOI: 10.9790/3008-1203044050